Cannabis Oil : Everything you need to know – Dosage Methods, Side Effects and Over-dosing

 I often get queries from people who are taking cannabis oil who are uncertain about the dosage. The two main extremes are folk who have been on a grain of rice once a day for three months but can’t understand why they aren’t seeing more results and others take too much to begin with and end up having unpleasant experiences.

Dosage is important. The idea behind the dosage amount is to get your body saturated with the oil as quickly as possible in order to see noticeable, speedy recoveries. The quicker you are able to get up to 1ml a day of oil, the quicker you begin to see the healing effects.

But everyone’s different. It doesn’t matter if you have used cannabis recreationally or not – everyone’s tolerance to the effects of cannabis oil is different and so it can take less than a month for some folk to achieve 1 ml a day and up to three months for others to get there. It’s important that everyone go at their own pace and not over or under dose themselves

Tip: Eat raw honey with the oil as it apparently helps your body to metabolize and absorb the THC and CBD’s more effectively and efficiently.

What Pills don’t Mix Well with Cannabis:

Blood Pressure Pills: If you are taking pills for high blood pressure, get your pressure checked regularly. The oil balances out your blood pressure and some people find they have to come off their blood pressure pills as they increase their cannabis oil dosage.

Blood Sugar Pills: Since cannabis has the potential to affect blood sugar levels, caution is advised when using medications that also effect blood sugar such as pharmaceuticals for diabetes.

Birth Control Pills: While more studies need to be done, there is a possibility that cannabis counteracts estrogen. Be cautious, or use an extra form of birth control, such as condoms, when consuming cannabis.

The following is a list of pharmaceuticals that have negative interactions with cannabis.

(The interesting thing is that the first three pharmaceuticals in this list can actually be replaced with cannabis instead of using both in tandem and risking increased side effects.)

Buprenorphine: Buprenorphine is an opioid that can be used to treat mild or chronic pain, or as a substance to help opioid addicts recover. Buprenorphine causes nervous central depression, so when combined with cannabis, side effects may cause respiratory distress, coma, or even death

Levonmethadyl acetate: Levomethadyl acetate is a synthetic opioid used to treat dependence on opioids. Using cannabis in tandem with levomethadyl acetate may lead to increased side effects such as drowsiness, dizziness, light-headedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Sever reactions may result in coma or even death on some occasions.

Sodium Oxybate: Sodium oxybate is a prescription drug that is used to treat excessive daytime sleepiness (EDS), which is a condition associated with narcolepsy. Side effects related to mixing sodium oxybate with cannabis are similar to those listed for interactions between levomethadyl acetate and cannabis. There is a potential for increased side effects of levomethadyl acetate such as drowsiness, dizziness, light-headedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Occasionally, severe reactions may result in coma and even death.



Different ways to get your dosage

  1. For severe, late stage cancer

This method is effective for people who are racing against time and need to begin seeing some results as a matter of urgency. This method is only sustainable if you are no longer working and are able to stay at home and sleep during the day.

Begin with taking a grain of rice sized dose of oil three times a day.

Every three to four days, double this dose. If doubling is too much – increase it as much as possible.

Keep doing this every three to four days until the dose becomes substantial, allow four to five days to increase the dose.

The benefits of this method

  • You quickly get up to 1 ml a day.
  • It’s very relaxing and you sleep a lot during the day and night which increases healing.
  • Your body has a continuous supply going through your blood stream throughout the day targeting mutated cells.

The Down Side

  • It can leave you feeling very drowsy and high and not able to get much done during the day. – including driving

2. A more moderate method

This is the method I used to cure my breast cancer as I couldn’t afford to be drowsy and high all day while caring for my toddler.

Begin by taking between a match head and a grain of rice size of oil just before bed. If you are working, double your dose over the weekend so that you are used to the dose by the time you start work on Monday.

It takes between 40 mins and 2 hours for the oil to kick in and the effect to start showing – I would recommend taking the oil and heading straight to bed as when the effects take hold, your mind can start working overtime and although you feel very relaxed, it can be hard to fall asleep.

Also, because you are taking a full dose in one singular go, it may take longer for you to adjust. Some people may only be able to increase their dose every two weeks.

The benefits of this method

  • You aren’t high during the day and so can function normally which makes it more sustainable to use.
  • If you don’t wait too long to go to bed after taking the oil you enjoy a great night’s sleep as cannabis oil has been shown to enhance your body’s ability to reach the deep state of sleep that is most beneficial for healing.

The Down Side

  • It leaves you feeling very drowsy in the morning as you are taking the full day’s dose in one go.
  • If you wake up during the night you can feel very wobbly and unstable after taking such a large singular dose.
  • It takes longer to get to 1ml a day.

3. For Pain Management

Take between a match head and a grain of rice sized dose before bed every night – increase this once a week until it’s a grain and a half sized dose.

Once you have been taking it at night for two weeks you can start taking between a match head and grain of rice size dose of oil when you are in pain. Allow 40 mins for it to take effect. If you are still in pain, take another match head more.

Once a week increase your dose until you are comfortable. Adjust this dose according to your requirements. If you are careful and take time to increase your tolerance, you need not feel high during the day.

The Benefits to this method

  • You are not only treating the pain but probably whatever is causing the pain.
  • Over time, as you learn to better manage your pain with the oil you can also start to come off other medications.

4. For long term illnesses

For people who are not terminal but who are suffering from diseases like Crohn’s Disease,  Lupus, etc.

Begin by taking a match head size of oil before bed.

After a week, increase this by half.

After two weeks increase it again until you are taking a grain and a half of rice sized dose.

Increase it again if you feel it is necessary.

(During the day, if you need to manage the pain, refer to method 3.)

Benefits of this method

  • You aren’t high during the day (unless managing pain)
  • You can build up your tolerance slowly
  • You eventually come off of most of your chronic meds.

5. Suppositories

Many people are severely affected by the  oil and have a very low tolerance for it. This makes getting yourself to the right dosage more challenging. However, there are ways around this.

Making the oil into a suppository is an excellent method – especially for people dealing with prostrate or colon issues but also for anyone battling to deal with the side effects of the oil – this is the way to go.

The link below gives excellent directions for making your own suppositories – you can use either concentrated oil mixed into coconut oil or you can use oil that has been made with coconut oil (mail me for this recipe:

Making cannabis oil suppositories:

Benefits of this Method

. You can take much more at a time without it affecting you so you can increase your dosage rapidly

Downsides of this Method

There is no downside to this method.

 Anxiety and Sensitivity to Side Effects

Some people find it harder to adapt to the effects of the oil than others. People who are using the oil to treat anxiety should also use this protocol as taking too much oil can aggravate anxiety.

If you are very sensitive and struggling to increase your dose then this method will be helpful. Dilute the concentrated oil into gently heated coconut oil- 1ml oil to 10 ml coconut oil. Once this is diluted, put it in the fridge to harden. Then take a small amount – a grain of rice size – at night. Once a week increase this by half until you are taking three or four rice grain sizes at night before bed.

If this is still too strong for you, dilute the oil more or take two weeks before increasing your dose.

What does taking the oil feel like?

  • A flushed feeling in the face – I think as a result of the increased blood flow to the brain.
  • Increased thirst – I think this is due to the detoxification process so make sure you drink WATER and not sugary crap!
  • A feeling of drowsiness and extreme relaxation.
  • Feeling a bit detached from your body.
  • Increased flow of thoughts and ideas
  • A general feeling of well-being and happiness
  • Increased hunger

How do you know you’ve taken too much?

  • Nausea and possibly vomiting
  • Dry mouth and intense thirst
  • Dizzy and very unstable and unbalanced and you may need the assistance of a wall or friend to walk
  • Possible Paranoia – a very real sense of fear or foreboding
  • Rare, but possibility of hallucinations
  • Heat feels like its beating out of your chest

What should you do if you’ve taken too much?

  • Remember no one has ever died from too much cannabis – Calm Down – you are going to be fine!
  • Take a big glass of water with you and go lie down until you feel better- it will pass in a few hours.
  • If you have to get up to go to the toilet or fetch more water remember to use the wall for balance or ask someone to help you – don’t underestimate how dizzy you might feel -this is especially important for frail and older people who can’t afford to fall and hurt themselves.
  • For people who suffer from the effects of paranoia, depending on the severity, it might be best to phone a trusted friend and not be alone during this time. Paranoia is a powerful psychological reaction that plays on your fears and insecurities and although it won’t physically harm you, it can be very unpleasant to have to go through alone. The same thing applies for hallucinations. In both cases, go to bed as soon as you can and try to sleep through it.

For my story go to:

How to make your own cannabis infused coconut oil:

How to make your own cannabis concentrate oil in South Africa:

To join our Facebook group for more ideas on how to use cannabis go to:

32 thoughts on “Cannabis Oil : Everything you need to know – Dosage Methods, Side Effects and Over-dosing

  1. Pingback: How to Make Cannabis Oil in South Africa – updated | Kitchen Cures

    • Good questions! With non-active oil (I assume you’ve used a cold extract method?) it’s easier to get your dose up because your body doesn’t’ have to learn to deal with the side effect of the activated THC, etc. As a preventative measure I would suggest getting your dose up to the size of two grains of rice and stay on that. It will be enough to stat combating any issues your body has and to protect against cancer, Alzheimer’s etc in the future.

      • No, if you are using it as a preventative you can use high CBD ratios instead – the CBD’s will help strengthen your immune system over time so it can effectively repair and protect the body. You want there to be some THC in your treatment because of the entourage effect and because it destroys cancer cells but you don’t have to get high to heal.

    • My husband has being taking it for a week and is struggling with the high effect. He can’t sleep because the room is spinning around and is very dizzy is thus normal until he gets used to it.

      • His tolerance is low so he will need to dilute the oil slightly (with coconut oil or olive oil) until the effects are not so strong. Once he’s used to that dose he can increase it. If he’s working during the week then he should increase on Friday night so if he’s still feeling the effects the next day he can sleep in until he feels better. Some people really struggle to get their tolerance up – if this is the case with your husband then look into suppositories. They are still effective and still go into the bloodstream but because it bypasses the liver it doesn’t make you feel high.

  2. Hi,in some pics we see cannibis oil that looks like “oil” in a bottle, and at other times we see a resin like substance in a syringe. What is the difference and which is more effective

    • Hi Leonie

      There are a variety of different methods for using cannabis. The dark resin – usually in a syringe is cannabis oil. This is highly concentrated is what I would recommend for someone with cancer or a serious health issue. A light liquid is usually a tincture – which is where the plant has soaked in alcohol for a few weeks – this is usually a fairly mild dose and is for less serious issues – but apparently helps effectively with pain. Another way of doing it is to do a ‘wash’ or ‘rinse’which is when they use a solvent like alcohol but instead of soaking the plant matter in it, they simply rinse the plant quickly with alcohol or oil – this is usually to get a THC dominant result. There are also other ways of making it – I know Bobby Greenhash has a different method entirely. From my experience the dark green/black resin is the most potent and most effective when treating cancer, the lighter medicines are usually not as concentrated and work well as complimentary medicine to the resin/oil or for treating long term illnesses like Lupus or Crohn’s Disease.
      If anyone has anything to add – please feel free!

  3. Hi There, I do not have cancer that I am aware of but am a 52 year old healthy female, peri-menopausal but do have HPV type 16 for around 15 years. I have had CIN 2 twice but both times the virus has gone after a Lletz and cone biopsy. I recently purchased the oil
    the dark black/greenish one and have been taking this (about the tip of a toothpick) every night. I have been sleeping so much better and seem to have more energy. I never feel high or hungry but take it just before I go to sleep. Will it help with my HPV and am I taking the correct dosage?

    • As far as I know the oil will definitely help. Apart from taking it orally you can also apply it directly to affected areas. (You can also mix the oil with coconut oil or with a bit of neem oil first before applying it). I would recommend you increase your dose to the size of a grain of rice – your tolerance should be at a point where this increase shouldn’t affect you but if you are unsure, do it over the weekend so you can sleep in if needs be. Because you have been taking it at night and you are taking a tiny amount you wont feel the affects of the high – so keep taking it just before bed and don’t underestimate how much healing benefit there is in a good night’s sleep! Just remember this is not a ‘quick fix’- you will need to keep taking it orally for a while to allow it to do it’s work. I had a quick look online and there are a few people who claim to have cured their HPV using the oil – so keep at it!

  4. Pingback: Cancer, Chronic Conditions & Cannabis Oil: THC vs CBD’s | Kitchen Cures


  6. Hi-I wanting to take this due to pain from arthritis but concerned it could increase my weight which wouldn’t be good on my joints ,

    • Cannabis oil is amazing for relieving pain. With regards to weight gain – you normally only get the munchies when you smoke cannabis, it has less effect when ingested. However, studies have shown that those who use cannabis have higher levels of good cholesterol and lower of the bad. Cannabis has also been shown to help treat insulin resistance and in general cannabis users tend to have smaller waistlines. One of the reasons people tend to get the munchies is that their blood sugar drops slightly but if you take the oil and go to bed you wont feel any of the side-effects.

  7. so u guys are saying that mariguana cures everything, uh? every illness you stated that the TCH and or CBD will cure . What hard evidence is there? There is no research to prove your information. While it may be very good for certain problems, it does Not mean that it will cure Everyhing. Hmmmm

    • Hi Lorena – I’m not sure where you read me saying cannabis cures everything but yes, cannabis has got many varied applications and I have used it to successfully help people dealing with all manner of dis-ease.
      Unfortunately due to its illegal status it has been difficult to get scientific studies and so for a large part we have had to rely on anecdotal evidence. However, the Science is starting to catch up and its proving what we already knew – that cannabis is effective for a large variety of different ailments. Also because if it’s bidirectional effects it is able to help many different issues without you having to take many different meds. So, no, I never said it cures everything but I’ve yet to find anything it doesn’t help with! However, everyone responds differently to cannabis and often it’s a case of playing around with the strain or thc to cbd ratio to achieve the full therapeutic benefits. I hope I have helped to clarify thus for you but please feel free to email me if you have any specific questions or concerns.

  8. Hi Kelly, with the medicinal stuff being almost legal, lots of people are jumping on the “let’s make some money” bandwagon, and distributors abound. They defend their product as being authentic but cannot tell you for example whether it is derived from Sativa or Indica, or the approx THC or CBD concentrations. My understanding is that Cannabis oil is not really a one-size-fits-all med, and a strong THC content may exacerbate certain conditions, like anxiety. Now that things are a little less cloak and dagger, can anyone tell me of a manufacturer that actually knows what they are doing?

  9. I am coming across lots of info regarding extraction of CBD form the plant using olive oil/coconut oil. Whats up with this. I was under the impression that a solvent(alcohol based) was necessary. Please can someone explain this to me or is it just another con. Also people advertising the therapeutic effects of CBD in Hemp oil. I thought Hemp had too low concentrations of anything to actually be meaningful.

  10. Hello, thank you for sharing this info about treating cancer with cannabis oil! I was diagnosed with breast cancer which was treated and have been ok for years. 6 years ago it came back as secondaries to my lungs! I’m in UK but plan to visit SA (home) in April and want to try this treatment. Please advise. Dudu

  11. Full plant extract ratio 1:1 THC:CBD — mix 5g co with 15 g coconut oil. 1 drop under tongue 2 or three times a day. for COPD.

    does this sound ok ?

  12. Pingback: How Much Cannabis Oil Per Day – Vape Juice Coronium

  13. Thank you so much for all you are doing to people in need.. Many of who are desperate to save a love one! .. My question is if your cancer is no longer showing than do you continue using the oil?.. If the cancer cells die do they come Back once you stop?.. Should you always maintain the oil in your body to keep cancer away?

    • Hi Rachel
      Yes, once the cancer is gone it’s considered a good idea to go on to a maintenance dose. This is a much smaller dose – a grain of rice for the concentrate oil and a teaspoon of cannabis infused coconut oil. It’s suggested you continue for a year after the cancer to ensure total healing and to prevent the cancer from returning but many people continue with the oil on a smaller dose indefinitely because of the health benefits – so it’s up to you how long afterwards you’d like to keep taking it for.

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